Drug-Induced Liver Injury: Pattern Recognition and Future Directions
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چکیده
منابع مشابه
Drug-Induced Liver Injury: Pattern Recognition and Future Directions
Drug-induced liver injury (DILI) remains a significant clinical challenge and is the leading cause of acute liver failure in most countries. An aging population that uses more medications, a constant influx of newly developed drugs and a growing risk from unfamiliar herbal and dietary supplements will make DILI an increasing part of clinical practice. Currently, the most effective strategy for ...
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Liver injury due to prescription and nonprescription medications is a growing medical, scientific, and public health problem. Worldwide, the estimated annual incidence rate of drug-induced liver injury (DILI) is 13.9-24.0 per 100,000 inhabitants. DILI is one of the leading causes of acute liver failure in the US. In Korea, the annual extrapolated incidence of cases hospitalized at university ho...
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Pattern recognition is one of the most important functionalities for intelligent behavior and is displayed by both biological and artificial systems. Pattern recognition systems have four major components: data acquisition and collection, feature extraction and representation, similarity detection and pattern classifier design, and performance evaluation. In addition, pattern recognition system...
متن کاملDrug-induced liver injury.
Drug-induced liver injury is a frequent cause of hepatic dysfunction. Reliably establishing whether the liver disease was caused by a drug requires the exclusion of other plausible causes and the search for a clinical drug signature. The drug signature consists of the pattern of liver test abnormality, the duration of latency to symptomatic presentation, the presence or absence of immune-mediat...
متن کاملDrug-induced Liver Injury.
Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal. It is important to recognize and remove the offending agent as quickly as possible to prevent the progression to chronic liver disease and/or acute liver failure. There are no definite risk factors for DILI, but pre-existing ...
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ژورنال
عنوان ژورنال: Gut and Liver
سال: 2016
ISSN: 1976-2283,2005-1212
DOI: 10.5009/gnl15114